Chemical Hazard Guidelines & Chemical- Specific Procedures Library

Chemical Hazard Guidelines & Chemical- Specific Procedures Library

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Standard Operating Procedures (SOPs) are intended to inform and educate laboratory personnel about hazards in their workplace and identify special handling procedures, engineering controls, and personal protective equipment (PPE) to prevent exposure. It is the responsibility of the Principal Investigator (PI) or designee to review and approve the SOP(s) ensuring that the protective equipment and procedures outlined are in place. All laboratory personnel must be trained on the SOP(s) applicable to their work before conducting hazardous activitites.

Laboratory Specific Standard Operating Procedures (SOPs)

Chemical identified as particularly hazardous substances (PHS), High hazard Substances (HHS) or those with unique "high-risk" hazards require a customized, laboratory-specific SOP. Refer to the information below for guidance on what should be included in a SOP.

Chemical Hazards Guidelines

EHRS developed chemical hazard guidelines that summarize general guidance for the safe handling of chemicals in a specific hazard class, such as flammable liquid or oxidizer. These guidelines DO NOT include specific lab procedures, the amount and concentration used, etc. In some cases, the safety guidelines will provide enough information for labs to work safely with all chemicals in that class. In other cases (with Particularly Hazardous Substances) additional lab specific written procedures are required.

  • * Means customization is required.  Use the SOP template to create a customized SOP.  Newer guidelines (after 1/22) may be utilized to supplemented and/or develop a lab-specific SOP.   

Physical Hazards

Chemical Hazard Guideline - Compressed Gases (rev. 1/2022)

Chemical Hazard Guideline - Corrosives (11/2022)

Chemical Hazard Guideline - Cryogens (rev. 1/2022)

Chemical Hazard Guideline - Flammable Liquids (rev. 5/2022)

Chemical Hazard Guideline - Organic Peroxide Formers (rev. 6/2022)

Chemical Hazard Guideline - Oxidizers (rev. 1/2023)

SOP-Pyrophoric Chemicals*

SOP-Reactive Liquids*

SOP-Reactive Solids*

SOP-Water Sensitive Chemicals*

Health Hazards

SOP-Acutely Toxic Chemicals* (Highly Hazardous Chemicals)

SOP-Acutely Toxic Gases* (Highly Hazardous Chemicals)

SOP-Carcinogens* (PHS)

Particularly Hazardous Substances* (PHS)

SOP-Reproductive Hazards* (PHS)

Specific Chemicals

Bromodeoxyuridine (BrdU)*






Chemical Hygiene Program